ACE
Other Endocrinology & Hormones Inhibitors
| Cat.No. | Product Name | Information | Product Use Citations | Product Validations |
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| S9666 | DX600 | DX600 is a specific inhibitor of angiotensin-converting enzyme 2 (ACE2) that does not cross-react with ACE. |
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| S8940 | MLN-4760 | MLN-4760 (compound 16) is a potent and selective inhibitor of human angiotensin-converting enzyme 2 (ACE2) with IC50 of 0.44 nM. This compound also inhibits bovine carboxypeptidase A (CPDA) with IC50 of 27 μM. |
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| E6037 | Perindopril | Perindopril (S-9490) is a brain-penetrating inhibitor of angiotensin-converting enzyme (ACE) with an IC50 of 0.048 μM for ACE-1. It exhibits anti-hypertensive, anti-inflammatory, and anti-fibrotic properties. |
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| E4900 | Enalapril | Enalapril(Eletriptan, Amprace, Vaseretic) is an inhibitor of angiotensin-converting enzyme (ACE), primarily used to treat hypertension, heart failure, and asymptomatic left ventricular dysfunction. It also attenuates frailty in aging mice. |
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| E2435 | Perindopril L-Arginine | Perindopril L-Argininel is a prodrug that is metabolised in the liver to its active diacid metabolite perindoprilat, which is rapidly and extensively absorbed, and become one of the highest tissue angiotensin-converting enzyme (ACE) affinities among the ACE inhibitors. | ||
| S3562 | Deserpidine | Deserpidine (Harmonyl), an alkaloid isolated from the roots of Rauwolfia canescens, is a competitive angiotensin converting enzyme (ACE) inhibitor, also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex. | ||
| E0863New | Talfirastide acetate | Talfirastide acetate (TXA127 acetate; Angiotensin (1-7) acetate; Ang-(1-7) acetate) is an endogenous heptapeptide of the renin–angiotensin system (RAS) with a cardioprotective role due to its anti‑inflammatory and anti‑fibrotic activities in cardiac cells. It inhibits purified canine ACE activity with an IC50 of 0.65 μM and also acts as a local synergistic modulator of kinin‑induced vasodilation by inhibiting ACE and promoting nitric oxide release. | ||
| E4876 | Lisinopril | Lisinopril(MK-521) is a potent inhibitor of angiotensin-1 converting enzyme (sACE-1) with an IC50 of 1.9 nM. It demonstrates significant efficacy in the management of hypertension and heart failure, potentially improving cardiovascular outcomes. | ||
| S2051 | Captopril | Captopril (SQ 14225, Capoten) is an angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 6 nM. |
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| S2099 | Temocapril HCl | Temocapril HCl (CS-622) is the hydrochloride of Temocapril, which is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension. |
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