NADPH-oxidase Inhibitors

Cat.No. Product Name Information Product Use Citations Product Validations
S5717 Acetohexamide Acetohexamide is an intermediate-acting, first-generation oral sulfonylurea with hypoglycaemic activity. It exerts the blood-glucose-lowering effects by stimulating the pancreatic beta cells to secrete insulin and by helping the body use insulin efficiently.
S4299 Dicoumarol Dicoumarol is a competitive NADPH quinone oxidoreductase (NQO1) inhibitor, and used as an anticoagulant by interfering with the Metabolism of vitamin K.
Adv Sci (Weinh), 2025, 12(7):e2411538
Redox Biol, 2024, 75:103292
Acta Pharmacol Sin, 2023, 1-13.
S1907 Metronidazole Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa.
Dis Model Mech, 2024, 17(10)dmm050900
Microorganisms, 2022, 10(7)1421
Elife, 2021, 10e69795
S5703 Carvedilol Phosphate Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimetic activity.
Res Pharm Sci, 2016, 11(5):419-427
Res Pharm Sci, 2015, 10(5):388-96
S9617 G6PDi-1 G6PDi-1 is an effective inhibitor of glucose-6-phosphate dehydrogenase (G6PD). This compound depletes NADPH and decreases inflammatory cytokine production.
EMBO J, 2023, e110620.
S6749 ASP-9521 ASP-9521 is a selective, orally bioavailable inhibitor of 17beta-hydroxysteroid dehydrogenase type 5 (17β-HSD5), also known as aldo-keto reductase family 1 member C3 (AKR1C3).
S0764 AKR1C1-IN-1 AKR1C1-IN-1 is a potent and selective inhibitor of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1) with Ki of 4 nM, 87 nM, 4.2 μM and 18.2 μM for AKR1C1, AKR1C2, AKR1C3 and AKR1C4, respectively.
S0468New AKR1C3-IN-1 AKR1C3-IN-1 is a highly potent inhibitor of aldo-keto reductaseAKR1C3 with an IC50 of 13 nM. It can be used in research targeting both breast and prostate cancer.