Vanillylacetone

Catalog No.S2371 Batch:S237101

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Technical Data

Formula

C11H14O3
Molecular Weight 194.23 CAS No. 122-48-5
Solubility (25°C)* In vitro DMSO 38 mg/mL (195.64 mM)
Ethanol 38 mg/mL (195.64 mM)
Water 10 mg/mL (51.48 mM)
In Vivo (Add solvents to the product individually and in order.)
Homogeneous suspension
CMC-NA
≥5mg/ml Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Vanillylacetone (NSC 15335) is similar in chemical structure to other flavour chemicals such as vanillin and eugenol and is used as a flavour additive in spice oils and in perfumery to introduce spicy aromas. This compound alleviates oxidative stress and inflammation, down-regulates NF-κB mediated signalling pathways. It acts as an anti-mitotic agent, and inhibits the growth of neuroblastoma cells.
Targets
NF-κB
In vitro

Vanillylacetone is similar in chemical structure to other flavour chemicals such as vanillin and eugenol. It is used as a flavour additive in spice oils and in perfumery to introduce spicy aromas. Fresh ginger does not contain this compound; cooking the ginger transforms gingerol, which is present, into it through a retro-aldol reaction. This chemical is likely the active constituent responsible for the antidiarrhoeal efficacy of ginger.

Protocol (from reference)

References

  • https://pubmed.ncbi.nlm.nih.gov/17880155/
  • https://pubmed.ncbi.nlm.nih.gov/30532634/

Sellecks Vanillylacetone Has Been Cited by 1 Publication

Palmitic Acid Accumulation Activates Fibroblasts and Promotes Matrix Stiffness in Colorectal Cancer [ Cancer Res, 2025, 85(10):1784-1802] PubMed: 39992719

RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.

SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.