Ethacridine lactate

Catalog No.S4945 Batch:S494501

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Technical Data

Formula

C18H21N3O4
Molecular Weight 343.38 CAS No. 1837-57-6
Solubility (25°C)* In vitro DMSO 69 mg/mL (200.94 mM)
Water 69 mg/mL (200.94 mM)
Ethanol 20 mg/mL (58.24 mM)
In Vivo (Add solvents to the product individually and in order.)
Homogeneous suspension
CMC-NA
≥5mg/ml Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Ethacridine lactate (Acrinol) is an aromatic organic compound based on acridine used as an antiseptic agent. This compound is also a poly(ADP-ribose) glycohydrolase (PARG) inhibitor.
Targets
PARG

Protocol (from reference)

References

  • https://pubmed.ncbi.nlm.nih.gov/27587383/
  • https://pubmed.ncbi.nlm.nih.gov/12318489/

Sellecks Ethacridine lactate Has Been Cited by 1 Publication

iPSC-based drug discovery identified the Hippo signaling pathway as a therapeutic target in the fibrosis of NPHP1-deficient nephronophthisis [ Stem Cell Res Ther, 2025, 16(1):489] PubMed: 40968381

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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.