iKIX1

Catalog No.S1991 Batch:S199101

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Technical Data

Formula

C10H8Cl2N4OS
Molecular Weight 303.17 CAS No. 656222-54-7
Solubility (25°C)* In vitro DMSO 61 mg/mL (201.2 mM)
Ethanol 1 mg/mL (3.29 mM)
Water Insoluble
In Vivo (Add solvents to the product individually and in order.)
Homogeneous suspension
CMC-NA
≥5mg/ml Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description iKIX1 is an antifungal agent and resensitises drug-resistant Candida glabrata to azole antifungals in vitro, which blocks the interaction between the CgGal11A KIX domain and the CgPdr1 activation domain (AD), the IC50 and Ki values are 190.2 μM and 18 μM, respectively.

Protocol (from reference)

References

  • https://pubmed.ncbi.nlm.nih.gov/26886795/

RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.

SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.