For research use only. Not for use in humans.

Anti-CCR7 / CD197 (R707)

Synonyms: R707 Cat.No.A2630 Purity:99%

Anti-CCR7 / CD197 (R707) is a fully human antibody targeting CCR7 signalling and function. It exhibits the potential to prevent acute graft-versus-host disease (aGVHD). MW: 145.36 KD.

Quality Control

Batch: A263001 Purity: 99% Protein concentration: 4.928mg/ml Endotoxin Level: ＜1EU/mg

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COA
SDS
Datasheet

Specificity

Name	Citation	CCR
Adaptavir (DAPTA)	3	+++

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation.
2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Anti-CCR7 / CD197 (R707) is a fully human antibody targeting CCR7 signalling and function. It exhibits the potential to prevent acute graft-versus-host disease (aGVHD). MW: 145.36 KD.
References	[1] https://pubmed.ncbi.nlm.nih.gov/30748092/

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

Molecular Weight	145.36
Isotype	Human IgG1
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Sellecks selected clones are more frequently applied. (data until September 2024)

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