Clone No.:PC-61.5.3
The PC-61.5.3 monoclonal antibody reacts with mouse IL-2Rα also known as CD25, Ly-43, p55, or Tac.The PC-61.5.3 antibody has been shown to inhibit the binding of IL-2 to both the low and high affinity IL-2 receptor forms. Additionally, the PC-61.5.3 antibody is commonly used to deplete CD4+FoxP3+ T regulatory cells in vivo.
| Molecular Weight | 150 kDa |
|---|---|
| Clone | PC-61.5.3 |
| Immunogen | IL-2-dependent cytolytic mouse T cell clone B6.1 |
| Isotype | Rat IgG1,λ |
| Application | in vivo regulatory T cell depletion,FCM |
| Purification | protein A |
| Sterility | 0.2 μM filtered |
| Formulation | PBS buffer, pH 7.0 |
| Storage | Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles |
*Literature analysis of various clone (for this target) products available on the market shows that Sellecks selected clones are more frequently applied. (data until September 2024)
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