For research use only. Not for use in humans.

Anti-PVR / CD155 (Ntx1088)

Synonyms: NTX-1088 Cat.No.A3167 Purity:99%

Anti-PVR / CD155 (Ntx1088) is a first-in-class potent monoclonal antibody targeting poliovirus receptor. It can be used in treatment of patients with locally advanced and metastatic solid tumours. MW: 145.86 KD.

Quality Control

Batch: Purity: 99% Protein concentration: 5.751mg/ml Endotoxin Level: ＜1EU/mg

Specificity

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation.
2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Anti-PVR / CD155 (Ntx1088) is a first-in-class potent monoclonal antibody targeting poliovirus receptor. It can be used in treatment of patients with locally advanced and metastatic solid tumours. MW: 145.86 KD.
References	[1] https://aacrjournals.org/cancerres/article/82/12_Supplement/5534/700576/Abstract-5534-NTX-1088-a-first-in-class-anti-PVR

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

Isotype	Human IgG1
Source	CHO
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Sellecks selected clones are more frequently applied. (data until September 2024)

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