For research use only. Not for use in humans.

Anti-Siglec-15 / CD33L3 (AB-25E9)

Synonyms: AB-25E9 Cat.No.A3054

Anti-Siglec-15 / CD33L3 (AB-25E9) is a humanised monoclonal antibody targeting sialic acid-binding immunoglobulin-like lectin 15 (Siglec-15). It may have potential as an anti-resorptive therapy for osteoporosis. MW :150 KD.

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Datasheet

Specificity

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation.
2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Anti-Siglec-15 / CD33L3 (AB-25E9) is a humanised monoclonal antibody targeting sialic acid-binding immunoglobulin-like lectin 15 (Siglec-15). It may have potential as an anti-resorptive therapy for osteoporosis. MW :150 KD.
References	[1] https://pubmed.ncbi.nlm.nih.gov/34216837/

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

Isotype	Human IgG1
Source	CHO
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Sellecks selected clones are more frequently applied. (data until September 2024)

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