For research use only. Not for use in humans.

Bleselumab (Anti-TNFRSF5 / CD40)

Synonyms: ASKP 1240 Cat.No.A2634 Purity:98%

Bleselumab (Anti-TNFRSF5 / CD40) is a human monoclonal antibody (mAb) targeting human CD40. It has the potential to prevent organ transplant rejection. MW: 150 KD.

Quality Control

Batch: A263401 Purity: 98% Protein concentration: 16.673mg/ml Endotoxin Level: ＜1EU/mg

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COA
SDS
Datasheet

Specificity

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation.
2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Bleselumab (Anti-TNFRSF5 / CD40) is a human monoclonal antibody (mAb) targeting human CD40. It has the potential to prevent organ transplant rejection. MW: 150 KD.
References	[1] https://pubmed.ncbi.nlm.nih.gov/31509331/

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	1453067-91-8
Molecular Weight	150
Isotype	Human IgG4PE
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Sellecks selected clones are more frequently applied. (data until September 2024)

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