For research use only. Not for use in humans.

Codrituzumab-MMAE

Cat.No.D4021 Purity:99%

Codrituzumab-MMAE, is an antibody-drug conjugate composed of an anti-GPC3 monoclonal antibody and a cytotoxic tubulin polymerase inhibitor conjugated through MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) type linker.

CAS No.

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Quality Control

Batch: D402101 Purity: 99% Protein concentration: 9.14mg/ml Endotoxin Level:

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Datasheet

Specificity

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation.
2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Codrituzumab-MMAE, is an antibody-drug conjugate composed of an anti-GPC3 monoclonal antibody and a cytotoxic tubulin polymerase inhibitor conjugated through MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) type linker.

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

ADC antibody	Codrituzumab
ADC cytotoxin	MMAE
Formulation	1xPBS
Storage	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Sellecks selected clones are more frequently applied. (data until September 2024)

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