For research use only. Not for use in humans.

Denintuzumab (Anti-CD19)

Synonyms: hBU 12 Cat.No.A2795 Purity:99%

Denintuzumab (anti-CD19) is a recombinant humanised anti-CD19 monoclonal antibody that can be used in the research of acute lymphoblastic leukaemia. Denintuzumab can be used to synthesise ADC antibody Denintuzumab Mafodotin (SGN-CD19A). MW: 145.0 kD.

Quality Control

Batch: A279501 Purity: 99% Protein concentration: 4.897mg/ml Endotoxin Level: ＜1EU/mg

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COA
SDS
Datasheet

Specificity

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation.
2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Denintuzumab (anti-CD19) is a recombinant humanised anti-CD19 monoclonal antibody that can be used in the research of acute lymphoblastic leukaemia. Denintuzumab can be used to synthesise ADC antibody Denintuzumab Mafodotin (SGN-CD19A). MW: 145.0 kD.
References	[1] https://pubmed.ncbi.nlm.nih.gov/27521873/

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	1630074-14-4
Molecular Weight	145
Isotype	Human IgG1
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Sellecks selected clones are more frequently applied. (data until September 2024)

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