For research use only. Not for use in humans.

Flanvotumab (Anti-TRP1 / TYRP1)

Synonyms: IMC-20D7S Cat.No.A2309

Flanvotumab (Anti-TRP1 / TYRP1) is a monoclonal antibody directed against the melanosomal membrane protein gp75 (or Tyrosinase-Related Protein 1 (TRP1)) with potential immunostimulatory and antineoplastic activities. MW: 145.5 kD.

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SDS
Datasheet

Specificity

Name	Citation	tyrosinase	monophenolase	diphenolase
Deoxyarbutin	0	++++
Hexylresorcinol	0	+++	++	+++
Arbutin	3	+
Aloin (Barbaloin)	9	✔

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation.
2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Flanvotumab (Anti-TRP1 / TYRP1) is a monoclonal antibody directed against the melanosomal membrane protein gp75 (or Tyrosinase-Related Protein 1 (TRP1)) with potential immunostimulatory and antineoplastic activities. MW: 145.5 kD.

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	1188277-05-5
Molecular Weight	145.5 kDa
Isotype	Human IgG1
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Sellecks selected clones are more frequently applied. (data until September 2024)

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