For research use only. Not for use in humans.

Gosuranemab (Anti-Tau)

Synonyms: BMS-986168; IPN007; BIIB092 Cat.No.A2692

Gosuranemab (Anti-Tau) is a humanised monoclonal antibody against the extracellular N-terminal of tau in the interstitial fluid (ISF) and CSF released by neurons. It has the potential for research of Alzheimer’s disease (AD). MW: 150 kD.

Quality Control

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SDS
Datasheet

Specificity

Name	Citation	Microtubule Associated	Others
Patupilone (Epothilone B)	17	+++
Lexibulin (CYT997)	8	++++
Epothilone A	6	++
CW069	8	+
Combretastatin A4	7	+++
CK-636	5	++
ABT-751 (E7010)	5	✔
Nocodazole	130	✔	Abl,Abl (E255K),Abl (T315I)
TAI-1	2	✔
INH6	0	✔
INH1	2	✔

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation.
2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Gosuranemab (Anti-Tau) is a humanised monoclonal antibody against the extracellular N-terminal of tau in the interstitial fluid (ISF) and CSF released by neurons. It has the potential for research of Alzheimer’s disease (AD). MW: 150 kD.
References	[1] https://pubmed.ncbi.nlm.nih.gov/35300725/

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	1788032-39-2
Molecular Weight	150
Isotype	Human IgG4SP
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Sellecks selected clones are more frequently applied. (data until September 2024)

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