For research use only. Not for use in humans.

Pidilizumab (Anti-PDCD1 / PD-1 / CD279)

Synonyms: CT 011 Cat.No.A3035

Pidilizumab (Anti-PDCD1 / PD-1 / CD279) is a humanised monoclonal antibody targeting human PD-1 (programmed cell death 1; PDCD1). It has immunomodulating and antitumour activities and can be used in treatment of metastatic melanoma. MW :144.48 KD.

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SDS
Datasheet

Specificity

Name	Citation	PD-1/PD-L1 interaction
PD-1/PD-L1 Inhibitor 3	13	+++
BMS-1	13	++
BMS-202	26	+
AUNP-12	3	✔

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation.
2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Pidilizumab (Anti-PDCD1 / PD-1 / CD279) is a humanised monoclonal antibody targeting human PD-1 (programmed cell death 1; PDCD1). It has immunomodulating and antitumour activities and can be used in treatment of metastatic melanoma. MW :144.48 KD.
References	[1] https://pubmed.ncbi.nlm.nih.gov/33559526/

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	1036730-42-3
Isotype	Human IgG1
Source	CHO
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Sellecks selected clones are more frequently applied. (data until September 2024)

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