For research use only. Not for use in humans.
Ruplizumab (Anti-TNFSF5 / CD40L / CD154)
Synonyms: BG 9588
Ruplizumab (Anti-TNFSF5 / CD40L / CD154) is a humanised monoclonal antibody targeting CD40L(TNF Receptor). It has the potential for systemic lupus erythematosus disease research. MW :145.68 KD.
Specificity
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation.
2. "✔" indicates inhibitory effect, but without specific value.
2. "✔" indicates inhibitory effect, but without specific value.
Mechanism of Action
| Description |
Ruplizumab (Anti-TNFSF5 / CD40L / CD154) is a humanised monoclonal antibody targeting CD40L(TNF Receptor). It has the potential for systemic lupus erythematosus disease research. MW :145.68 KD.
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References |
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Product Details
| CAS No. | 220651-94-5 |
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| Isotype | Human IgG1 |
| Source | CHO |
| Formulation | 100 mM Pro-Ac, 20mM Arg, pH5.0 |
| Storage | Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. |
Comparison of Clones for
*Literature analysis of various clone (for this target) products available on the market shows that Sellecks selected clones are more frequently applied. (data until September 2024)
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