For research use only. Not for use in humans.
Sibeprenlimab (Anti-TNFSF13 / APRIL / CD256)
Synonyms: VIS649
Sibeprenlimab (Anti-TNFSF13 / APRIL / CD256) is a fully humanised IgG2κ monoclonal antibody that targets the B-cell growth factor APRIL (TNFSF13), with the potential to treat IgA nephropathy (IgAN). MW: 145.5 KD.
Specificity
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation.
2. "✔" indicates inhibitory effect, but without specific value.
2. "✔" indicates inhibitory effect, but without specific value.
Mechanism of Action
| Description |
Sibeprenlimab (Anti-TNFSF13 / APRIL / CD256) is a fully humanised IgG2κ monoclonal antibody that targets the B-cell growth factor APRIL (TNFSF13), with the potential to treat IgA nephropathy (IgAN). MW: 145.5 KD.
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Product Details
| CAS No. | 2382896-07-1 |
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| Molecular Weight | 145.5 kDa |
| Isotype | Human IgG2SA |
| Source | CHO |
| Purification | AKTA |
| Sterility | 0.2 μM filtered |
| Formulation | 100 mM Pro-Ac, 20mM Arg, pH5.0 |
| Storage | Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. |
Comparison of Clones for
*Literature analysis of various clone (for this target) products available on the market shows that Sellecks selected clones are more frequently applied. (data until September 2024)
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