For research use only. Not for use in humans.

Utomilumab (Anti-TNFRSF9 / 4-1BB / CD137)

Synonyms: PF 05082566 Cat.No.A2620 Purity:99%

Utomilumab (Anti-TNFRSF9 / 4-1BB / CD137) is a fully human IgG2 monoclonal antibody targeting the T-cell costimulatory receptor 4-1BB/CD137. It can be used for the research of relapsed/refractory follicular lymphoma (FL), non-Hodgkin lymphomas (NHL). MW :142.78.

Quality Control

Batch: A262001 Purity: 99% Protein concentration: 7.24mg/ml Endotoxin Level: ＜1EU/mg

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COA
SDS
Datasheet

Specificity

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation.
2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Utomilumab (Anti-TNFRSF9 / 4-1BB / CD137) is a fully human IgG2 monoclonal antibody targeting the T-cell costimulatory receptor 4-1BB/CD137. It can be used for the research of relapsed/refractory follicular lymphoma (FL), non-Hodgkin lymphomas (NHL). MW :142.78.
References	[1] https://pubmed.ncbi.nlm.nih.gov/32144134/

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	1417318-27-4
Molecular Weight	142.78
Isotype	Human IgG2SA
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Sellecks selected clones are more frequently applied. (data until September 2024)

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