For research use only. Not for use in humans.

Vadastuximab (Anti-Siglec-3 / CD33)

Synonyms: Anti-Human CD33 Recombinant Antibody Cat.No.A2357 Purity:99%

Vadastuximab (Anti-Siglec-3 / CD33) is a humanised monoclonal antibody targeting CD33. Vadastuximab can be used to synthesise an ADC compound, Vadastuximab talirine. MW : 150 KD.

Quality Control

Batch: A235701 Purity: 99% Protein concentration: 3.51 mg/ml Endotoxin Level: ＜1EU/mg

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COA
SDS
Datasheet

Specificity

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation.
2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Vadastuximab (Anti-Siglec-3 / CD33) is a humanised monoclonal antibody targeting CD33. Vadastuximab can be used to synthesise an ADC compound, Vadastuximab talirine. MW : 150 KD.

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	1436390-64-5
Molecular Weight	150 kDa
Isotype	Human IgG1
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Sellecks selected clones are more frequently applied. (data until September 2024)

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