Home Endocrinology & Hormones RAAS AT1 receptor-Selective Inhibitors

AT1 receptor-Selective Inhibitors

  • AT1 receptor
  • AT2 receptor
  • ACE
  • Renin
Cat.No. Product Name Information Selective / Pan IC50 / Ki
S1578 Candesartan Candesartan is an angiotensin II receptor antagonist with IC50 of 0.26 nM. Selective AT1 receptor, IC50: 0.26 nM
S4102 Eprosartan Mesylate Eprosartan is a nonpeptide angiotensin II receptor antagonist, [3H]-eprosartan binds to the AT1 receptor with KD of 0.83 nM in rat vascular smooth muscle cells. Selective AT1 receptor, Kd: 0.83 nM
S1507 Irbesartan Irbesartan (SR-47436, BMS-186295) is a highly potent and specific angiotensin II type 1 (AT1) receptor antagonist with IC50 of 1.3 nM. Selective AT1 receptor, IC50: 1.3 nM
S3057 Azilsartan Medoxomil Azilsartan Medoxomil is a potent angiotensin II type 1 (AT1) receptor antagonist, inhibits the RAAS, with an IC50 of 2.6 nM, exhibits >10,000-fold selectivity over AT2. Selective AT1 receptor, IC50: 2.6 nM
S3046 Azilsartan Azilsartan is an angiotensin II type 1 (AT1) receptor antagonist with IC50 of 2.6 nM. Selective AT1 receptor, IC50: 2.6 nM
S1359 Losartan Potassium (DuP 753) Losartan is an angiotensin II receptor antagonist, competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM. Selective AT1 receptor, IC50: 20 nM
S1604 Olmesartan Medoxomil Olmesartan Medoxomil is a compound which is hydrolyzed to olmesartan that is a selective AT1 subtype angiotensin II receptor antagonist. Selective