CXCR4-Selective Antagonists
- CXCR2
- CXCR4
| Cat.No. | Product Name | Information | Selective / Pan | IC50 / Ki |
|---|---|---|---|---|
| S2912 | WZ811 | WZ811 is a highly potent competitive CXCR4 antagonist with EC50 of 0.3 nM. | Selective | CXCR4, EC50: 0.3 nM |
| S8030 | Plerixafor (AMD3100) | Plerixafor is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively. | Selective | CXCR4, IC50: 44 nM |
| S3013 | Plerixafor 8HCl (AMD3100 8HCl) | Plerixafor 8HCl (AMD3100 8HCl) is the hydrochloride of Plerixafor, a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively. | Selective | CXCR4, IC50: 44 nM |
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