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ErbB3 Inhibitors

  • EGFR/ErbB1
  • HER2/ErbB2
  • ErbB3
  • ErbB4
Cat.No. Product Name Information Selective / Pan IC50 / Ki
S2192 AZD8931 (Sapitinib) AZD8931 (Sapitinib) is a reversible, ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 with IC50 of 4 nM, 3 nM and 4 nM in cell-free assays, more potent than Gefitinib or Lapatinib against NSCLC cell, 100-fold more selective f Pan ErbB3, IC50: 4 nM