Home Metabolism -DNA Damage/DNA Repair PPAR PPARγ-Selective Inhibitors | Agonists | Antagonists

PPARγ-Selective Inhibitors | Agonists | Antagonists

  • PPARα
  • PPARβ/δ
  • PPARγ
  • PPARδ
Cat.No. Product Name Information Selective / Pan IC50 / Ki
S2871 T0070907 T0070907 is a potent and selective PPARγ inhibitor with IC50 of 1 nM, with a >800-fold selectivity over PPARα and PPARδ. Selective PPARγ, IC50: 1 nM
S2505 Rosiglitazone maleate Rosiglitazone, a member of the thiazolidinedione class of antihyperglycaemic agents, is a high-affinity selective agonist of the peroxisome proliferator-activated receptor-γ. Selective PPARγ, IC50: 42 nM
S2590 Pioglitazone Pioglitazone is a selective peroxisome proliferator-activated receptor-gamma (PPARgamma) agonist, used to treat diabetes. Selective
S2915 GW9662 GW9662 is a selective PPAR antagonist for PPARγ with IC50 of 3.3 nM, with at least 100 to 1000-fold functional selectivity in cells with PPARγ versus PPARα and PPARδ. Pan PPARγ, IC50: 3.3 nM
S7484 FH535 FH535 is a Wnt/β-catenin signaling inhibitor and also a dual PPARγ and PPARδ antagonist. Pan