Home Metabolism Retinoid Receptor RAR-Selective Agonists

RAR-Selective Agonists

  • RAR
  • RXR
Cat.No. Product Name Information Selective / Pan IC50 / Ki
S4627 TTNPB (Arotinoid Acid) TTNPB (Arotinoid Acid) is a potent RAR agonist, and inhibits binding of [3H]tRA with IC50 of 5.1 nM, 4.5 nM, and 9.3 nM for human RARα, β, and γ, respectively. Selective RARγ, IC50: 9.3 nM; RARγ, IC50: 9.3 nM; RARβ , IC50: 4.5 nM; RARα, IC50: 5.1 nM
S4260 Tamibarotene Tamibarotene is a synthetic retinoic acid receptor (RAR) agonist with high specificity for RARα and RARβ over RARγ. Selective
S1276 Adapalene Adapalene is a dual RAR and RXR agonist, used in the treatment of acne. Pan
S1653 Tretinoin Tretinoin, which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells. Pan