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Sodium Channel

Autre Transmembrane Transporters Inhibiteurs

CFTR CRM1 Calcium Channel Proton Pump P-gp ATPase Potassium Channel CD markers GLUT Amino acid transporter
N° de cat. Nom du produit Informations Citations dutilisation du produit Validations de produit
S1811 Amiloride HCl Amiloride HCl is a selective T-type Calcium Channel blocker, an epithelial Sodium Channel blocker and a selective inhibitor of urokinase plasminogen activator (uPA)(Ki=7 μM).
J Extracell Vesicles, 2024, 13(4):e12426
Virus Res, 2024, 339:199258
J Clin Invest, 2023, 10.1172/JCI163402
S2874 Camostat Mesilate Camostat (FOY-305, FOY-S980) is a trypsin-like protease inhibitor, inhibits airway epithelial Sodium Channel (ENaC) function with an IC50 of 50 nM, less potent to trpsin, prostasin and matriptase.
CNS Neurosci Ther, 2024, 30(6):e14822
Elife, 2022, 11e77444
Antiviral Res, 2022, 202:105325
S1614 Riluzole Riluzole is a glutamate release inhibitor with neuroprotective, anticonvulsant, anxiolytic and anaesthetic qualities.
Neurotherapeutics, 2023, none
J Endocr Soc, 2023, 7(10):bvad117
Front Bioeng Biotechnol, 2022, 10:855755
Verified customer review of Riluzole
S3024 Lamotrigine Lamotrigine (BW-430C, LTG) is a novel anticonvulsant drug for inhibition of 5-HT with an IC50 of 240 M and 474 M in human platelets and rat brain synaptosomes, and this compound is also a Sodium Channel blocker.
iScience, 2024, 27(10):110862
Front Pharmacol, 2024, 15:1489888
Nat Commun, 2022, 13(1):2785
S2560 Amiloride HCl dihydrate Amiloride HCl dihydrate (MK-870 hydrochloride dihydrate) is a potent epithelial Sodium Channel (ENaC) blocker, used in the management of hypertension and congestive heart failure.
iScience, 2025, 28(3):111931
J Immunother Cancer, 2024, 12(11)e009805
Adv Sci (Weinh), 2022, 9(29):e2202039
S1693 Carbamazepine Carbamazepine (Carbatrol, NSC 169864) is a sodium channel blocker with IC50 of 131 μM in rat brain synaptosomes.
J Immunother Cancer, 2024, 12(11)e009805
mBio, 2022, e0217721
Front Pharmacol, 2021, 12:749930
S2454 Bupivacaine HCl Bupivacaine HCl binds to the intracellular portion of voltage-gated Sodium Channel and blocks sodium influx into nerve cells, used for treating cardiac arrhythmias.
Int J Mol Sci, 2019, 20(17)
J Steroid Biochem Mol Biol, 2017, 172:89-97
Sci Rep, 2015, 5:17772
S2525 Phenytoin Phenytoin (Di-Hydan, Dihycon, Dilabid, Diphedan, Diphenat, Diphenylan, Diphenylhydantoin, Hydantol, Lehydan, NSC 8722) is an inactive voltage-gated Sodium Channel stabilizer.
Cancer Cell, 2025, 43(4):776-796.e14
Cell Mol Gastroenterol Hepatol, 2023, 16(2):223-242
Front Cell Neurosci, 2023, 17:1175895
S4058 Ropivacaine HCl Ropivacaine HCl (LEA-103) is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.
Elife, 2021, 10e65962
Cancer Discov, 2020, CD-20-0160
Oncol Rep, 2020, 43(5):1659-1668
E8150 Amiloride Amiloride (MK-870) is the first potent inhibitor of epithelial sodium channel (ENaC), inhibiting δβγ ENaC with an IC50 of 2.6 μM. It is also a typical blocker of PC2(TRPP2) channels and can be used in the research to study Autosomal dominant polycystic kidney disease (ADPKD).
Sci Rep, 2025, 15(1):18633
INTERNATIONAL DOCTORAL SCHOOL OF THE USC, 2023,
Johns Hopkins University, 2022,