Histone Acetyltransferase Activators

Featured Inhibitors
Inhibitors (28)
Chemical (1)
Activators (2)

Cat.No.	Product Name	Information	Product Use Citations	Product Validations
S0022	YF-2	YF-2 is a highly selective, blood-brain-barrier permeable activator of histone acetyltransferase (HAT). In In vitro assays, this compound has activity versus CBP, PCAF, and GCN5 with EC50 of 2.75 μM, 29.04 μM and 49.3 μM, respectively. It also increases p300 activity.	J Extracell Vesicles, 2025, 14(2):e70042 J Exp Clin Cancer Res, 2022, 41(1):77
E1107	CTB	CTB is a p300 activator and the lowest docked energy for this compound and p300 is 7.72 kcal/mol.

Cat.No.

Product Name

Information

Product Use Citations

Product Validations

S0022

YF-2

YF-2 is a highly selective, blood-brain-barrier permeable activator of histone acetyltransferase (HAT). In In vitro assays, this compound has activity versus CBP, PCAF, and GCN5 with EC50 of 2.75 μM, 29.04 μM and 49.3 μM, respectively. It also increases p300 activity.

J Extracell Vesicles, 2025, 14(2):e70042

J Exp Clin Cancer Res, 2022, 41(1):77

E1107

CTB

CTB is a p300 activator and the lowest docked energy for this compound and p300 is 7.72 kcal/mol.