MAO

Isoform-selective Products

Cat.No. Product Name Information Product Use Citations Product Validations
S4246 Tranylcypromine HCl Tranylcypromine HCl is a monoamine oxidase inhibitor, which inhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and Human Liver Microsomes, respectively.
Sci Bull (Beijing), 2024, S2095-9273(24)00799-0
Cell Rep, 2023, 42(6):112566
Biomolecules, 2023, 13(3)521
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S9464 Tranylcypromine Sulfate Tranylcypromine Sulfate is an irreversible inhibitor of monoamine oxidase (MAO) with a rapid onset of activity.
Int J Mol Sci, 2022, 23(8)4213
Nan Fang Yi Ke Da Xue Xue Bao, 2021, 41(3):418-423
Nat Methods, 2020, 17(5):495-503
S3212 Moclobemide (Ro 111163) Moclobemide (Ro 111163) is a MAO-A (5-HT) inhibitor with an IC50 of 6.1 μM.
J Gerontol A Biol Sci Med Sci, 2022, 77-8:1485-1493
Biol Reprod, 2021, ioab182
Pharmacol Biochem Behav, 2018, 166:13-20
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S2102 Rasagiline Mesylate Rasagiline Mesylate (TVP-1012,(R)-AGN1135 mesylate,TVP1012 mesylate) is a new MAO-B inhibitor for the treatment of idiopathic Parkinson's disease.
J Immunother Cancer, 2024, 12(11)e009805
Front Pharmacol, 2022, 13:1004215
EMBO Mol Med, 2021, e13929
S3690 Pargyline hydrochloride Pargyline is an irreversible inhibitor of monoamine oxidase (MAO)-B with Ki values of 13 and 0.5 μM for time-dependent inhibition of the activity of MAO-A and -B, respectively.
J Immunother Cancer, 2024, 12(11)e009805
Genome Med, 2021, 13(1):168
Cancer Lett, 2017, 398:12-21
S4033 Sennoside A Sennoside A (NSC 112929), a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.
Sci Adv, 2022, 8(15):eabm3471
Front Pharmacol, 2020, 11:566099
S2339 Paeonol Paeonol (Peonol), a phenolic compound extracted from Chinese herbs Paeonia suffruticosa (moutan cortex) and Cynanchum paniculatum, inhibits MAO with an IC50 of about 50 μM.
Biochem Biophys Res Commun, 2023, 656:86-96
Int J Biol Sci, 2019, 15(11):2497-2508
S4717 Isatin Isatin (2,3-Indolinedione) is an endogenous MAO inhibitor with an IC50 of 15 μM and more active against MAO-B than MAO-A.
Adv Sci (Weinh), 2025, 12(28):e2417318
Cell Rep, 2022, 38(13):110559
S5269 J147 J147, a curcumin derivative, is a potent neurogenic and neuroprotective compound developed for the treatment of neurodegenerative conditions associated with ageing.
J Mol Histol, 2023, 54(6):725-738.
E2632 Norharmane Norharmane (Norharman) is a potent and selective monoamine oxidase A (MAO-A) inhibitor with a Ki of 3.34 μM.
Adv Sci (Weinh), 2025, 12(35):e04038