NMDAR Agonists
| Cat.No. | Product Name | Information | Product Use Citations | Product Validations |
|---|---|---|---|---|
| S7072 | NMDA (N-Methyl-D-aspartic acid) | NMDA (N-Methyl-D-aspartic acid) is a specific agonist for the NMDA receptor, mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. Phase 4. |
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| S3624 | Quinolinic acid | Quinolinic acid (pyridine-2,3-dicarboxylic acid, QUIN), a neuroactive metabolite of the kynurenine pathway, is an agonist of N-methyl-D-aspartate (NMDA) receptor. | ||
| S6907 | Rapastinel (GLYX-13) | Rapastinel (GLYX-13, BV-102, TPPT-amide) is a partial agonist of N-methyl-D-aspartate receptor (NMDAR) that targets a glycine site, and it has long-lasting antidepressant effects. | ||
| S6224 | (R)-Serine | (R)-Serine is the R-enantiomer of serine, which is used in the biosynthesis of proteins. This compound acts as obligatory coagonist at the glycine site associated with the N-methyl-D-aspartate subtype of glutamate receptors (NMDAR) and has a cardinal modulatory role in major NMDAR-dependent processes including NMDAR-mediated neurotransmission, neurotoxicity, synaptic plasticity, and cell migration. | ||
| S3203 | D-Alanine | D-Alanine (Ala, (R)-Alanine, Ba 2776, D-α-Alanine, NSC 158286) is an endogenous co-agonist at the glycine site of the N-methyl-d-aspartate (NMDA) receptor. | ||
| S4702 | Sarcosine | Sarcosine (N-methylglycine, Sarcosinic acid, Methylaminoacetic acid, Methylglycine) is a competitive inhibitor of the type I glycine transporter (GlyT1) and an NMDAR co-agonist. |
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