Hedgehog/Smoothened Agonists
| Cat.No. | Product Name | Information | Product Use Citations | Product Validations |
|---|---|---|---|---|
| S7779 | SAG (Smoothened Agonist) Hydrochloride | SAG (Smoothened Agonist) HCl is a cell-permeable Smoothened (Smo) agonist with an EC50 of 3 nM in Shh-LIGHT2 cells. |
|
|
| S3042 | Purmorphamine | Purmorphamine (Shh Signaling Antagonist VI), which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo with IC50 of ~ 1.5 μM in HEK293T cell and also is an inducer of osteoblast differentiation with EC50 of 1 μM. Purmorphamine can reduce both basal and induced autophagy. |
|
|
| S6384 | SAG (Smoothened Agonist) | SAG (Smoothened Agonist) is a potent agonist of Smoothened (Smo). Smoothened Agonist induces firefly luciferase expression in Shh-LIGHT2 cells with an EC50 of 3 nM. |
|
Products are for research use only. Not for human use. We do not sell to patients.
©Copyright 2013 Selleck Chemicals. All Rights Reserved.